FOXO4 antibody (AA 455-505)

Catalog No. ABIN7453088

The Rabbit Polyclonal anti-FOXO4 antibody has been validated for WB. It is suitable to detect FOXO4 in samples from Human.

Quick Overview for FOXO4 antibody (AA 455-505) (ABIN7453088)

Target: FOXO4 (Forkhead Box O4 (FOXO4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXO4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FOXO4 Antibody

Binding Specificity: AA 455-505

Purpose: Rabbit anti-FOXO4 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 455 and 505

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FOXO4

Target: FOXO4 (Forkhead Box O4 (FOXO4))

Alternative Name: FOXO4

Background: Background: FOXO4 (fork-head box O4) is a fork-head DNA-binding domain containing protein and functions as a transcription factor involved in the regulation of the insulin signaling pathway. FOXO4 binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. It also down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes, and is involved in the negative regulation of the cell cycle [taken from the Universal Protein Resource (UniProt) P98177].

Gene ID: 4303

NCBI Accession: NP_005929

UniProt: P98177

Pathways: Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation